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LCAM centre among best in Europe

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15 December 2015

The van Leeuwenhoek Centre for Advanced Microscopy (LCAM), a collaboration of the Netherlands Cancer Institute, the AMC-UvA and the UvA’s Faculty of Science, is according to Euro-BioImaging one of the leading microscopy centres in Europe. The centre has therefore been officially endorsed as a node of this European consortium.

Euro-BioImaging is an emerging European partnership seeking to use Europe’s wide-ranging bioimaging expertise as efficiently as possible. With this quality seal, LCAM has attained the highest qualification in the development and application of advanced microscopy and imaging analysis and the provision of technology to users. A total of 28 European microscopy centres were declared nodes.

According to director Dorus Gadella, ‘It is Europe’s only designated “flagship node” in functional imaging microscopy.’ He explains: ‘functional imaging is the direct visualization and quantification of molecular processes in living cells with fluorescent biosensors. For instance, the interaction, movement and conformation changes of biomolecules and structures in cells. Or how external signals are processed by cells and how DNA is transcribed in the cell nucleus.’


Euro-BioImaging consortium

The declaration of the 28 European microscopy centres is a momentous step in the realisation of the European Strategy Forum on Research Infrastructure (ESFRI) Euro-BioImaging Roadmap. The ESFRI is a strategic instrument to develop the scientific integration of Europe and to strengthen its international outreach. The Euro-BioImaging consortium aims to build an infrastructure of wide-ranging, state-of-the-art imaging technologies. Thanks to its open access structure, it will in future provide life scientists in Europe and beyond with access to sophisticated facilities for biological, molecular and medical research.

Microscopy in the Netherlands

ESFRI quality seals have been awarded to nine centres in the Netherlands, placing our country, the technique’s birthplace, among Europe’s bioimaging leaders. With this European recognition, the prominence of the Dutch research tradition in this field has been confirmed. The Dutch centres are united in the NL BioImaging Advance Microscopy roadmap, coordinated by the University of Amsterdam.

LCAM Advanced Microscopy Course

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LCAM Advanced Microscopy Course

June 23-27, 2014

This course is organized by the Leeuwenhoek Centre for Advanced Microscopy (LCAM) and provides an in-depth view of specific advanced imaging techniques used at imaging centers of AMC, NKI and  FNWI.  The course focuses fully on intensive hands-on practical sessions and interactive discussions with experts in the various microscope techniques. On the final day participants present their own research topic and discuss which techniques should be implemented in their project.

During the course participants will visit the imaging centres of three institutes in Amsterdam, the NKI (Dutch Cancer Institute), the FNWI (UvA Science Park) and the AMC. In each institute the part will focus in depth on specific advanced imaging techniques.


– Measuring intra- and inter-molecular protein interactions using FRET and FLIM
– Confocal microscopy methods including spinning disk (CLSM)
– Superresolution microscopy

– Confocal quality control
– Correlative microscopy (bridging fluorescence microscopy and electron microscopy)
– Usage of fluorophores such as FlAsH/ReAsH 

Target audience:
PhD students and postdocs. An introduction course like the Basic Microscopy course is a prerequisite for the Advanced Microscopy Course.

Course organizers:
AMC Ron Hoebe, Eric Reits, Jan Stap, Henk van Veen
FNWI Dorus Gadella, Joachim Goedhart, Mark Hink, Erik Manders
NKI Lenny Brocks, Kees Jalink, Lauran Oomen


More information and application:
From Eric Reits / / tel. +31 (0)20 566 6259

LCAM Website restyled

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Today the LCAM website got restyled. Please let me know what you think about the new look!